Overproduction of intestinal lipoprotein containing apolipoprotein B-48 in Psammomys obesus: impact of dietary n-3 fatty acids
نویسندگان
چکیده
منابع مشابه
Impact of process parameters in the generation of nanoemulsions containing omega 3 fatty acids and α-tocopherol
Nanoemulsion is an alternative and promising approach to overcome insolubility and bioavailability problems of bioactive compounds. In this study, the sonication parameter for preparing nanoemulsions with high α- tocopherol and linolenic acid content were optimized by using response surface methodology and their stability were evaluated during 2 months’ storage. The response surface analysis re...
متن کاملImpact of process parameters in the generation of nanoemulsions containing omega 3 fatty acids and α-tocopherol
Nanoemulsion is an alternative and promising approach to overcome insolubility and bioavailability problems of bioactive compounds. In this study, the sonication parameter for preparing nanoemulsions with high α- tocopherol and linolenic acid content were optimized by using response surface methodology and their stability were evaluated during 2 months’ storage. The response surface analysis re...
متن کاملEffects of Dietary Conjugated Linoleic Acid and n-3 Fatty Acids on the Performance, Carcass Traits and Small Intestinal Morphology of Broiler Chickens
An experiment was conducted on broiler chickens to study the effects of conjugated linoleic acid (CLA), fish oil, both at 7% of the diet, or their mixtures at 3.5% of the diet, on the performance, carcass traits and intestinal morphology of broiler chickens. The chicks fed with 7% fish oil or 7% CLA diets, were found to have an inferior weight gain in grower and finisher phases, respectively. A...
متن کاملCellular aspects of intestinal lipoprotein assembly in Psammomys obesus: a model of insulin resistance and type 2 diabetes.
Although postprandial hypertriglyceridemia is a major contributing factor in the development of atherosclerosis, little information is available on the effect of insulin resistance and diabetes on intestinal fat transport. The aim of the present study was to examine intracellular events that govern lipid transport and apolipoprotein (apo) B-48-containing lipoprotein assembly in the small intest...
متن کاملHyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48-containing lipoproteins in humans.
OBJECTIVE Whereas postprandial hyperlipidemia is a well-described feature of insulin-resistant states and type 2 diabetes, no previous studies have examined intestinal lipoprotein production rates (PRs) in relation to hyperinsulinemia or insulin resistance in humans. METHODS AND RESULTS Apolipoprotein B-48 (apoB-48)-containing lipoprotein metabolism was examined in the steady-state fed condit...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2006
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-006-0315-3